Biostatistics Advance Access originally published online on July 14, 2005
Biostatistics 2006 7(1):115-129; doi:10.1093/biostatistics/kxi044
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Estimation in regression models with externally estimated parameters
Department of Biostatistics, Columbia University, 6th floor, 722 West 168th Street, New York, NY 10032, USA to166{at}columbia.edu
Department of Mathematics and Statistics, Wright State University, Dayton, OH 45435, USA
* To whom correspondence should be addressed.
In many regression applications, some of the model parameters are estimated from separate data sources. Typically, these estimates are plugged into the regression model and the remainder of the parameters is estimated from the primary data source. This situation arises frequently in compartment modeling when there is an external input function to the system. This paper provides asymptotic and bootstrap-based approaches for accounting for all sources of variability when computing standard errors for estimated regression model parameters. Examples and simulations are provided to motivate and illustrate the ideas.
Keywords: Bootstrap; Compartment models; PET imaging
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
F. Imamura, P. F Jacques, D. M Herrington, G. E Dallal, and A. H Lichtenstein Adherence to 2005 Dietary Guidelines for Americans is associated with a reduced progression of coronary artery atherosclerosis in women with established coronary artery disease Am. J. Clinical Nutrition, July 1, 2009; 90(1): 193 - 201. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. S. Milak, A. J. Severance, R. T. Ogden, J. Prabhakaran, J.S. D. Kumar, V. J. Majo, J. J. Mann, and R. V. Parsey Modeling Considerations for 11C-CUMI-101, an Agonist Radiotracer for Imaging Serotonin 1A Receptor In Vivo with PET J. Nucl. Med., April 1, 2008; 49(4): 587 - 596. [Abstract] [Full Text] [PDF] |
||||

